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Size-dependent activation of CAR-T cells

 Last Update: 2022-08-16
 Source: Internet
 Author: User

Summary

As the targeting of chimeric antigen receptor (CAR) T cells expands to a variety of cancers, autoimmune diseases, viral infections, and fibrosis, there is a growing need to identify novel antigens and design CARs that can be efficiently activated b.

However, the lack of understanding of the molecular mechanisms by which antigens activate CARs limits the rational selection of antigens and the design of CA.

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