Six months after the new coronavirus infection, the antibody is still stable in the human body

This newspaper in Shanghai, September 17 (Reporter Meng Yandi) recently, Shanghai Jiao university medical school affiliated with Ruijin Hospital National Translational Medical Center (Shanghai) related research has made the latest progress: protective neutral antibodies in the new coronavirus infection six months after the stable presence in the human body. Vaccines based on the virus that caused this year's outbreak of neo-coronary pneumonia should be equally effective against the current new coronavirus variant.
studies have shown that the body can produce antibodies and T-cells that respond to the new coronavirus after infection, but it is not clear how long these immunity can last, and the results of different teams are inconsistent. But the emergence of a second case of viral infection after the first viral infection has been cured, raising doubts about post-infection immunity and the ability of vaccines to prevent new coronavirus infections.
antibodies persist in the human body after a new coronavirus infection? In order to clarify the answer to this question, the National Translational Medicine Center of Ruijin Hospital, affiliated with Shanghai Jiao transportation university medical school, Shanghai Hematology Research Institute, National Key Laboratory of Medical Genomics, Shanghai Public Health Clinical Center and China Food and Drug Inspection Research Institute carried out long-term monitoring of people infected with neo-crown pneumonia.
researchers analyzed the expression levels of IgG antibodies in plasma samples from patients 2 weeks to 1 month, 1 to 2 months and 6 to 7 months after infection, and found that in plasma samples infected for 6 to 7 months, anti-neo-coronavirus IgG antibodies decreased from 2 weeks to 1 month and 1 to 2 months after infection, but remained at a high level. The researchers further analyzed the levels of new coronavirus and antibodies in plasma samples 2 weeks to 2 months and 6 to 7 months after infection and found that highly active neo-coronavirus mesoth antibodies were present in all samples, and that there was no difference in the level of meso antibodies in plasma samples from 2 weeks to 2 months and 6 to 7 months. The researchers also analyzed the presence of memory T cells for the new coronavirus in the blood of people who recovered six to seven months after infection, and found that CD4 and CD8T cells that responded to the new coronary antigen were present in all test samples.
results show that protective neutral antibodies and memory T cells remain stable in the human body six months after the new coronavirus infection.
the virus that caused this year's outbreak of neo-crown pneumonia is the 614D new coronavirus, but the recent emergence of 614G mutant strains makes the new coronavirus more contagious. Since the current vaccines against the new coronavirus are based on the 614D virus, the ability of these vaccines to produce antibodies to the 614G virus has heightened concerns and doubts.
to answer these questions, the researchers further analyzed the ability of antibodies taken from plasma samples to the 614G analog virus. They found that although most patients were infected with the 614D new coronavirus six months ago, their plasma samples had the same ability to median the 614D and 614G new coronavirus, suggesting that those infected with the 614D virus were also immune to the 614G virus, and speculated that the new coronavirus based on 614D should be trustworthy.
, the study was published in the Journal of the Chinese Academy of Engineering, "Medical Frontiers."