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Simcere Pharmaceuticals declares new drug for Alzheimer's disease

 Last Update: 2021-12-28
 Source: Internet
 Author: User

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On December 14, CDE's official website showed that Simcere/Vivoryon Therapeutics' new Alzheimer's disease drug PQ912 was reported for the first time in China

From: CDE official website

Varoglutamstat (PQ912) is an oral small molecule inhibitor of glutamyl peptide cyclase (QPCT)

Varoglutamstat plays a role in the early pathogenesis of the disease by preventing the formation of this toxic variant, so it has the potential to prevent neuronal damage

Neurotoxic amyloid N3pE can trigger AD-related pathological pathways, including Aβ oligomer formation, neuroinflammation, and tau-mediated neurotoxicity

The two products introduced by Simcere during the same period both target N3pE

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