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Significantly reduces the risk of triple-negative breast cancer recurrence of Keytruda combination Phase 3 clinical results published

 Last Update: 2022-05-02
 Source: Internet
 Author: User

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On February 10, 2022, Merck & Co.

TNBC is an aggressive type of breast cancer that occurs in 10-15% of breast cancer patients with a higher risk of disease recurrence within the first five years after diagnosis

Keytruda works by boosting the body's immune system's ability to help monitor and fight tumor cells

The trial met its primary endpoint of pathological complete response (pCR) at the first interim analysis: pCR was observed in 64.

Image source: Reference [2]

The trial also assessed the key secondary endpoint of overall survival (OS)

References:

[1] Pivotal Phase 3 Data for Keytruda® (pembrolizumab) in High-Risk Early-Stage Triple-Negative Breast Cancer (TNBC) Published in the New England Journal of Medicine.

[2] Schmid et al.

(Original abridged)

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