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Chinese scholars have made important progress in the research of swimming micro-nano robots in the treatment of gliomas |
China News Service, Harbin, March 29 (Zhang Yifang, reporter Shi Yifu) Harbin Institute of Technology announced on the 29th that the research team of Professor He Qiang and Professor Wu Zhiguang from the Micro and Nano Technology Research Center of the school has realized the first time that swimming micro and nano robots can treat brain gliomas.
Glioblastoma (GBM) is one of the most difficult to treat cancers.
How to make drugs break through the blood-brain barrier, achieve active targeted delivery of drugs, and improve the efficacy of drugs on gliomas has become a bottleneck problem in the medical field of gliomas for a long time.
In response to this problem, the research team has developed a swimming micro-nano robot (Neutrobot) based on immune cells in the body, which is prepared by neutrophils phagocytosing E.
The swimming micro/nano robot can effectively and stably carry paclitaxel and other anti-cancer drugs, and rely on the self-developed control system to guide the swimming micro/nano robot to the brain area.
These research results establish a swimming micro-nano robot based on immune cells as a potential precision therapy for glioma for the systemic treatment of glioma.
The research results were published online in the journal Science Robotics with the title "Dual-responsive biohybridneutrobots for active target delivery" (Dual-responsive biohybridneutrobots for active target delivery).