Shanghai to develop vaccine-containing eggs experts say can fight bird flu after consumption

A "universal first aid vaccine" that can prevent a variety of infectious diseases will be the next direction of research and development for researchers in Shanghai, and the public will "eat" eggs to fight hepatitis B against avian influenzaAn egg that will keep people fighting bird flu, hepatitis and bacteria in a short time will no longer be a sci-fi sceneYesterday, at the international seminar on infectious disease prevention and control measures held in Shanghai, Fudan University Medical College,"d'Itsa revealed that an "all-round first aid vaccine" that can prevent a variety of infectious diseases will be the next direction of research and development for researchers in Shanghai, in addition, the relevant experts also revealed that they will try to use genetically modified and other means to integrate the vaccine into eggs, the public "eat" eggs can fight hepatitis B against avian influenzaIt also avoids intestinal bacterial infection
" is like having an emergency hemorrhage belt"Wen Yumei academician yesterday to the future of the "all-powerful first aid vaccine" an image metaphor, "in the first time to temporarily improve the immunity of people." Wen Yumei revealed that the new vaccine can be called omnipotent because its prevention principle and traditional vaccine is completely different, it is not a certain pathogen microorganism (such as bacteria, rikers, viruses, etc.) and its metabolites, the implementation of artificial detoxification, inactivation or the use of genetic engineering methods to make automatic immunoagents against the bacteria, but before the attack of infectious diseases, a short time before the human "armed."And accept the temporary "arming" is the body's "
healthguardian" immune system"Universal vaccine" can use DNA, alum and polysaccharides can be very good to induce the internal immune response of the human drug, so as to avoid human infection with influenza or avian influenza, and even avoid bacterial infection in the intestinesBefore the advent of conventional vaccines, "these non-specific immunotherapy drugs that stimulate internal immune responses can be used at least to 'first aid'." "
for the future development of the new "first aid vaccine" process, Wen Yumei proposed that an international cooperative research fund could be set up to conduct animal infection experiments on such vaccines, to study the effects of immune response strains and viruses in animals, especially newborn and elderly animalsUsing egg yolks to make special oral liquidat yesterday's international seminar, Wen Yumei also revealed that the use of eggs to produce antibodies passive immune technology is also a future research project, it is possible to achieve the production of antibodies through eggs to directly respond to infectious diseases such as avian influenzaThe difference between active and passive immunity is that the former refers to injecting a detoxifying vaccine or seedling to stimulate the body to produce antibodies, while the latter is directly injected with protective external antibodies, a positive, a passive, "passive is also an emergency." Wen Yumei saidFor the principle of egg production antibodies, China's disease Prevention and Control Center Hou Yunde academician explained that is the first egg chicken after vaccination and other special immune treatment, so that the egg egg production of egg yolk will have anti-infectious diseases of immunoglobulin is also antibodies, and then, re-use special separation technology, refining related immunoglobulin, you can use oral methods to obtain immune effect In terms of proteins, if the protein is fermented by yeast to produce some immune stimuli, it can also be used to improve immunity by oral means, resistance to infections such as viruses and bacteria Will significantly reduce the price of drugs
Wen Yumei finally admitted that the egg "all-round" vaccine is only in the initial research and development state, from the real production for clinical use is still a very long way to go, which must overcome technical problems but also to overcome financial difficulties There are many advantages of producing antibodies from eggs, one of which is its cost, once the technology matures, according to the hen within a year each egg can be produced 300 to calculate, so rich in medicinal protein sources for mass production of related drugs to provide the possibility This will significantly reduce the prices of drugs and become a boon to the general public Meaning jump out of the traditional thinking of needles to prevent infectious diseases
at this moment, the constantly mutated cunning virus esquire the body's "
health guardian" - the immune system because it can not identify intruders in a timely manner and failure, and ultimately cause these viruses to go straight into the long-term In the case of avian influenza, who has warned that a mutation in the virus is "inevitable" and that a race against time has begun Earlier this year, medical experts found mutated strains of the bird flu virus in two Egyptian patients infected with the virus, which may have become resistant to Tamiflu, the most widely used anti-bird flu drug WHO officials say the new strains of the H
5 N
1 virus are not yet strong enough to trigger a massive bird flu outbreak, but as such mutations continue to mount, scientists need to rethink current treatments At the same time, the "big enemy" at present, the traditional vaccine is very "slow", generally need at least a few months cycle to be developed, for example, after the SARS outbreak, China basically completed the SARS virus inactivated vaccine pre-clinical research spent more than 6 months of efforts During this time, people's health will be greatly threatened In this regard, Fudan University School of Medicine academician Wen Yumei said that the relevant parties should support the practical application of research projects, can jump out of the inherent thinking of a vaccine to prevent an infectious disease, the development of an emergency vaccine that can stimulate the body's internal immune response, to prevent infectious diseases in the population out of control The release "vaccine" egg six questions and six answers
since the role is the egg yolk in the egg, then eat the yolk directly can fight avian influenza? A: No Using special separation techniques, the immune globulin in special egg yolks that can fight against infectious diseases is isolated and refined into related immunoglobulins, so that the effects of immunity can be obtained by oral method Can eating hard-boiled eggs fight against avian flu? A: No " It's also useless to cook "For people may have questions about egg production antibody technology, China's disease prevention and control center Of the Hou Yunde academician introduced that the eggs contain active ingredients only when it has active activity, want to cook to eat to fight infectious diseases is impossible At the same time, Hou Yunde revealed that the current difficulty of this technology is the process of switching from chicken to egg Is there a contradiction between the two theories that the avian influenza virus can be transmitted through eggs and can fight avian influenza through eggs? A: No contradiction Many poultry, such as chickens, turkeys, pearl chickens, quails, ducks, geese, etc can be infected with avian influenza, turkey and chicken are the most susceptible, morbidity and mortality are high But eggs that can fight avian influenza are produced by chickens that have been given special immune treatment, such as vaccination, and immunoglobulin in egg yolks can fight infectious diseases Is all-round vaccine eggs omnipotent? A: It's not everything Omnipotence is not omnipotent, Fudan University School of Medicine, Wen Yumei academician admitted that the "all-powerful vaccine" effect although for the prevention of a variety of germs appear all-powerful, but because its targeted is not strong, so the effect is not particularly good Is there a global precedent for producing antibodies from eggs? A: The UK has experimented It is reported that not long ago, British scientists have bred hens carrying human genes, they can produce eggs can contain a variety of special proteins, the practice is to make human genes and hen DNA combined The hen therefore produces a protein that has a medicinal effect, which can enter the egg What are the technical difficulties in producing antibodies from eggs? A: Facing security and other issues For the related new technology, China's Disease Prevention and Control Center Hou Yunde also admitted that whether it is the egg production antibodies related technology, or can be used as an oral vaccine genetically modified plant technology, are currently facing the test of safety and other issues Previous studies by foreign scientists have shown that people artificially alter DNA to grow genetically modified chickens, but this chicken after a generation or two, the ability to produce special proteins For non-natural genetically modified products, there has been a persistent view that the risk of man-made genetic engineering is greater than the technology used so far Because many of the damage is irreversible, it must be prevented "Research on GM is very cautious." Hou Yunde said (According to the Oriental Morning Post)