Shanghai study finds new solution to oral cancer treatment

treatment of oral cancer has a new therapeutic weaponYesterday, the 9th People'sHospital affiliated with Shanghai Jiaotong University Medical Schoolrevealed to the public that the National Natural Science Foundation of China key project research led by Chen Wantao researcher scored a major breakthrough, the study found and confirmed that the topological enzyme-II and other genes are effective molecular targets for the diagnosis and treatment of oral cancer molecules, can carry out "individualized" shooting of oral cancer cellsMalignanttumorin our country has become the number one killer ofhealthendangering people's lives, and the diagnosis of oral cancerstandardis still dependent on traditional otomorphology changes, and the treatment of drugs are not targeted, so thespecifictoy oftumor is not high, the toxic side effects are also largerThe research team, led by Professor Chen Wantao, has successfully developed a personalized gene chip that can judge the diagnosis, metastasis and resistance of oral scale cancer molecules through four years of research, combining modern biochips, functional genomics and proteomics techniques and methodsThrough the in-depth study of the function of oral cancer proliferation, drug resistance and metastasis-related genes, medical experts have found and confirmed that topological enzyme-II, metformin receptor-beta, cell cycle protein 1, nucleogene-B and Ebp1 are effective molecular targets for oral cancer treatment, and have maximized the therapeutic effect oftumorchemotherapy Clinical application has proved that the new combination chemotherapy scheme designed with topological enzyme-II as the main drug, the therapeutic effect is significantly higher than that of other traditional chemotherapy schemes, and has been applied to the clinic as the preferred chemotherapy scheme The new therapy has been popularized in more than a dozen medical units in China (Chen Zuliang Chen Liyu)