Shanghai birth is smaller than bacteria "capsules" expected to be drug slow release delivery

sick to take medicine 3 times a day, because the drug in the body will soon be metabolized; Reporters yesterday from the Chinese Academy of Sciences Shanghai Silicate Research Institute was informed that scientists in the world for the first time successfully prepared a nano-scale hollow ball with up to 4 layers of structure, these layers of "capsules" even smaller than bacteria, the results of the research recently published in the international authoritative journal "German Applied Chemistry." The industry believes that such structures have good application prospects for the delivery of future drugsIn the nanospace, it is the hot direction of international scientific research to control the shape of various nanomaterials by artificial meansBut before, people master the nano-hollow ball preparation technology is still stuck in the single-layer ball levelShanghai silicate institute Wang Wenzhong researcher led the team, suddenly this hollow ball's internal level record to 4 layers, and can be adjusted by the reaction parameters, free to make a single layer, double layer, three layer son or four layers of hollow ball, its diameter is only 150 to 300 nanometers, between the layer and layer gap only about 40 nanometers, equivalent to a hair silk diameter of 1/2000, even invisible to the naked eye also want to drill in the pastNumerous experiments have found that this seemingly incredible "work" can be produced by cheap raw materials, simple methodsPour a glass of warm water about 60 degrees Celsius, add a certain concentration of surface actuators, pour in a blue copper sulphate solution, and vitamin C as a reducing agent, and drop some alkaline sodium hydroxide to adjust the acidity - the whole process takes only 5 to 10 minutesAt this time, with an electron microscope to observe, a large number of nano-scale small vesicles appear, while the generation of countless copper oxide individuals, will automatically direct "stand" to these vesicle templatesAs more and more copper oxides "stand" into dense formations, the sacized shell becomes more and more dense, eventually becoming a hollow ballIts wall structure is one, the stability is goodExperts said that the multi-layer shell hollow ball structure is expected to achieve new functions and applications in terms of catalysis and carrierFor example, the shell between the layers may be filled with the same or different kinds of pharmaceutical preparations, etc, into the normal metabolic process of the organism, the outer shell is first metabolized, released the drug, and then each layer is metabolized one by one, the drug is gradually released, so that the duration of the effect increasesNot only that, because the "capsule"-like drug vectors are nanoscale, they can react more effectively at the molecular cell level"This multi-layered shell hollow ball is a new hollow structure, and electron microscopes strongly confirm this particular kind of structure, " said the foreign reviewer of German Applied ChemistryThis structure will be of interest to researchers in many fields and will have many potential applications..."(reproduced from Liberation Daily)