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    Home > Active Ingredient News > Immunology News > Serum amyloid A to albumin ratio as a potential biomarker for predicting systemic lupus erythematosus activity, severity and poor prognosis

    Serum amyloid A to albumin ratio as a potential biomarker for predicting systemic lupus erythematosus activity, severity and poor prognosis

    • Last Update: 2022-03-04
    • Source: Internet
    • Author: User
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    This is a prospective study of the predictive value of SAR for active SLE, severe active SLE, and poor prognosis in SLE
    .


    To evaluate the predictive value of serum amyloid A to albumin ratio (SAR) in active systemic lupus erythematosus (SLE), severe active SLE and poor prognosis in SLE


    This is a prospective study of the predictive value of SAR for active SLE, severe active SLE, and poor prognosis in SLE


    From January 2018 to March 2020, 230 patients with SLE were diagnosed in Taihe Hospital of Traditional Chinese Medicine.


    All SLE patients were divided into active SLE group and stable SLE group according to whether SLEDAI≥5
    .


    When testing baseline clinical data between the two groups, 11 factors showed significant differences (Figure 1)


    All SLE patients were divided into active SLE group and stable SLE group according to whether SLEDAI≥5


    Figure 1

    Figure 1

    Our findings suggest that SAR has a high predictive value for active SLE, severe active SLE, and poor prognosis in SLE
    .


    High SAR, high ACR, high TG, low C3 and positive anti-dsDNA were shown to be independent influencing factors of active SLE


    Our findings suggest that SAR has a high predictive value for active SLE, severe active SLE, and poor prognosis in SLE


    Source: Zhao L, Zhang Q, Feng Z, Zhang J, He F.
    Serum amyloid A-to-albumin ratio as a potential biomarker to predict the activity, severity, and poor prognosis of systemic lupus erythematosus.
    J Clin Lab Anal.
    2022 Feb 10:e24282.
    doi: 10.
    1002/jcla.
    24282.
    Zhao L, Zhang Q, Feng Z, Zhang J, He F.
    Serum amyloid A-to-albumin ratio as a potential biomarker to predict the activity, severity, and poor prognosis of systemic lupus erythematosus.
    J Clin Lab Anal.
    2022 Feb 10:e24282.
    doi: 10.
    1002/jcla.
    24282.
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