 Home > Biochemistry News > Biotechnology News > Scientists have successfully drawn the "methylation blueprint" of microglia in the human brain

Scientists have successfully drawn the "methylation blueprint" of microglia in the human brain

 Last Update: 2022-01-08
 Source: Internet
 Author: User

Tags

immune system defense

what journal article

Search more information of high quality chemicals, good prices and reliable suppliers, visit www.echemi.com

In the central nervous system, microglia play a very key role in development, aging, brain homeostasis, and pathological mechanisms.

Microglia are the brain’s own immune cells.

DNA methylation is the main form of epigenetic regulation, which determines the pattern of genes being turned on or off in a variety of situations over time; in the article, researchers donated to 22 donors of different ages The microglia isolated from the brain tissues after death were analyzed.

The researchers pointed out that microglia can exhibit DNA methylation characteristics that are different from other cells in the central nervous system, but differences between individuals (rather than differences in brain regions) have a greater impact on changes in DNA methylation.

In summary, the results of this study show that although based on a relatively small number of samples, the methylation characteristics of microglia are responsive to changes between individuals, so the microglia observed at the transcriptomics level The heterogeneity of cells plays a very important role

Note: The original text has been deleted

Original source:

Lot D.

This article is an English version of an article which is originally in the Chinese language on echemi.com and is provided for information purposes only. This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed description of the concern or complaint, to service@echemi.com. A staff member will contact you within 5 working days. Once verified, infringing content will be removed immediately.

Related Products

L-Ascorbate-2-Monophosphate Feed Grade

CAS No.: 109620-90-8

Feed Grade

Potassium Sorbate from reliable manufacturer

CAS No.: 590-00-1

Food Grade

Doxycycline Hydrochloride

CAS No.: 10592-13-9

Pharmaceutical Grade

Hot Tags

united states jobs(223)

jobs united states(236)

1 year treasury(277)

1 year subscription(296)

single use technology(195)

announcements today(81)

ups united states(221)

united states logo(227)

80 20 company(94)

healthy food name(42)

Hot Articles

The source of this page with content of products and services is from Internet, which doesn't represent ECHEMI's opinion. If you have any queries, please write to service@echemi.com. It will be replied within 5 days.

Moreover, if you find any instances of plagiarism from the page, please send email to service@echemi.com with relevant evidence.