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In a recent study published in the international journal Nature Communications, scientists from the Federal Institute of Technology (EPFL) in Lausanne, Switzerland, studied the discovery of hidden special estrogen-like polyps in breast epithal cells. Estrogen is an important hormone that plays a key role in the development and physiology of the breast and is also involved in the development of breast cancer, and like all hormones, estrogen exerts corresponding biological effects by binding to specific subjects that target cells.
Now, researchers have found that nearly half of the intra-cavity mammary epithelial cells that do not express estrogen receptors actually express them at lower levels, and in this study, researchers have found that different parts of the estrogen receptor may play a different role in cancer-inducing tube breast cells, depending on the level of estrogen receptors in the cells, and that estrogen-dependent activity has more or less an effect on cell function.
In addition, the researchers found that estrogen-like bodies actually work in both directions, stimulating the growth and expansion of breast cells in young mice, but inhibiting the growth of breast cells during pregnancy in mice.
The researchers concluded that the findings of this paper are of great importance in clarifying the role of Er alpha in the development of breast cancer, which raises the question of whether these ER false negative breast cells will eventually turn into estrogen-positive or negative breast cancer, although this will require more in-depth research later by scientists. (Bio Valley)