Scientists have discovered a pathway that extends the life of nematodes by 500%!

You know, this extension is not 20% or 50%, but 500%!how did this discovery come about? First, the scientists chose nematodes as their subjectsIt's a slender worm, one of the most commonanimal models used by biologistsSince the animal's normal lifespan is only 3-4 weeks, we will soon see changes in the life of any gene that can extend lifeIn the study, scientists focused on two known signaling pathways, one insulin signaling pathway and the other toRIn past studies, these two pathways have been found to be associated with the life span of nematodes, which can increase their lifespan by about 100 percent and 30 percent, respectivelyhow would changing both pathways affect the life span of nematodes? The researchers made a try, and the results were surprising to them -- "the synergy between the two pathways was crazy."scientists have concluded that the results suggest that there must be a special link between the two pathways behind themFurther digging, they found that this longevity was associated with mitochondriaThis is the "energy factory" in the cell, and for more than a decade, studies have shown that this organometer is associated with longevityIf the mitochondria are dysfunctional, it can cause a series of aging-related phenomenaillustration of this study (Photo: Source: Supplied, 1)In the study, scientists have identified a key longevity regulator, called CYC-2.1, a cytochromeStudies have shown that reducing the expression of CYC-2.1 activates the "non-folding protein reaction" in the mitochondria and promotes mitochondrial divisionThis significantly extends the life of nematodesresearchers also point out that although these findings come from nematodes, similar pathways are relatively conservativeIn the future, they plan to explore the future of the discovery References: MDI BiologicalS ScientistS Scientist Sexplorers Extend Lifespan by 500 Percent, Retrieved January 9, 2020, from https://mdibl.org/press-release/mdi-biological-scientists-identify-pathways-that-extend-lifespan-by-500-percent/ original title: 500 years again: This pathway discovered by scientists, extending the life of nematodes by 500%! Note: The original text has a limitation