Scientists have developed a new technology, scTRIP, that promises to speed up cancer diagnosis
-
Last Update: 2021-02-19
-
Source: Internet
-
Author: User
Search more information of high quality chemicals, good prices and reliable suppliers, visit
www.echemi.com
In a recent study published in the international journal Nature Biotechnology, scientists from institutions such as the European Molecular Biology Laboratory developed a cheap and fast way to examine genetic differences in a single cell that performs better than existing technologies in terms of the information it receives, a new approach that promises to be a new standard for single-cell research and could be used to clinically diagnose a variety of diseases, including cancer.Researcher Ashley Sanders says the new method we've developed could study genetic changes in a single cell, or hopefully change mutation detection, a technique called single-cell triple-channel processing that could help study genetic variations in DNA in a single cell and directly determine genetic mutations in information journals;The researchers then used scTRIP technology to test leukemia cells in the patient's body, and in the sample, the researchers found that the mutations found in patients using the new technology were four times the level of variation detected by standard clinical diagnosis, including a clinically related displacement loss. In addition, the researchers observed catastrophic chromosomal platoons, which are often missed during the initial leukemia diagnosis and can occur when a chromosome breaks and is re-pasted together in sequence.Researcher Tobias Marschall said the initial results showed that the new method was significantly superior to the existing method, which is much faster and much cheaper than the current method used to reveal genetic variations in single cells, which may make clinical sense; now researchers are expanding the scope of this approach to analyze different forms of leukemia and assess its potential clinical effectiveness. Since the heterogeneity of samples is well studied at the single-cell level, researchers around the world are working to develop new technologies to improve the information received, current techniques can reveal how different cells respond to therapy, and so far, research and applications have focused on determining the level of RNA in cells;ScTRIP technology, which combines information from three different channels in a single cell's genome code, could help reveal the complete map of DNA rearration in a single cell, and now, using it, researchers can solve a series of questions about how a cell in the body is different from any cell at the time of cancer, and scTRIP technology can help researchers directly determine the specific mutation processes that occur in cells, resulting in new genetically different cell populations. Later researchers also plan to delve into the mutations that occur in different human cells and assess the effects of these differences on human diseases. (Bio Valley Bioon .com)
This article is an English version of an article which is originally in the Chinese language on echemi.com and is provided for information purposes only.
This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of
the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed
description of the concern or complaint, to
service@echemi.com. A staff member will contact you within 5 working days. Once verified, infringing content
will be removed immediately.