Scientists have confirmed that sleeping 6-7 hours a night can prevent dementia

Tuo Jintai, a professor of neurology at Huashan Hospital affiliated with Fudan University, and Tan Lan Clinical Research Team, a professor of neurology at Qingdao University, found in a large clinical cohort study of nearly a thousand people that frequent daytime sleep deprivation, lack of sleep at night, or excessive sleep can increase the risk of cognitive impairment, while sleeping 6-7 hours a night can reduce the risk of cognitive impairment. The findings were published recently in the Journal of Alzheimer's disease and dementia.
In this study, the researchers first established a large database of clinical studies and biological samples of cognitive impairment, based on the establishment of the cohort (Chinese Alzheimer's biomarkers and lifestyle studies), to explore in depth the effects of various sleep characteristics on pathophysiological changes in Alzheimer's disease, the most common type of dementia. For the first time, researchers have confirmed the U-shaped relationship between nighttime sleep time and Alzheimer's pathology in middle-aged and elderly people: sleep deprivation or excess can promote abnormal deposition of amyloid protein in the body, which is a common pathogen and a key factor in the formation and development of Alzheimer's disease, and one of the core pathological characteristics of Alzheimer's disease. Daytime dysfunction , such as frequent daytime sleep, can also promote abnormal deposition of amyloid proteins in the body. The optimal sleep pattern was 6-7 hours of sleep at 10 p.m. each night, with the lowest levels of abnormal deposition of amyloid protein in the brain.
At the same time, the researchers used evidence-based medicine to fine-tune the evidence system for the link between sleep and the risk of cognitive impairment, including Alzheimer's disease, and found that 10 sleep characteristics (disorders) contribute to cognitive impairment, six of which are supported by moderate-intensity evidence, including insomnia, sleep division, daytime dysfunction, extended incubation periods, rapid eye movement sleep behavior disorders, and excessive bedtime. Further dose response analysis found a U-shaped relationship between nighttime sleep duration and Alzheimer's risk: the optimal nighttime sleep duration may be between 5.6 and 7 hours. The risk of cognitive impairment increases significantly when sleeping less than 4 hours or more than 10 hours at night.
" study not only confirmed the U-shaped relationship between nighttime sleep time and Alzheimer's disease at the biomarker level for the first time, but also biologically confirmed that sleep characteristics increase the risk of Alzheimer's disease by affecting amyloid deposition. In order to prevent cognitive impairment and dementia, attention should be paid to sleep management, Tulip said. (Source: Sun Guogen Huang Xin, China Science Journal)
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