Scientists have discovered a special drug that can effectively treat leukemia and lymphoma
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Last Update: 2019-12-13
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Source: Internet
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Author: User
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MEDICAL NETWORK DECEMBER 13 (UPI) -- IN A STUDY PUBLISHED IN THE INTERNATIONAL JOURNAL NATURE MEDICINE ENTITLED "A ELECTIVE BCL-XL PROTAC DEGRADER DEGRADER DAS AND POTENT ANTITUMOR ACTIVITY", SCIENTISTS FROM INSTITUTIONS SUCH AS THE UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER HAVE FOUND A NEW, SAFE NEW GENERATION OF DRUGS THAT MAY HELP WARD UP MULTIPLE TYPES OF LEUKEMIA AND LYMPHOMA IN ADULTS researcher Dr Robert Hroma said the new class of drugs, called PROTAC, could be useful for cancer patients because it targets BCL-XL, the survival protein necessary to act on cancer cells, after a drug that previously targeted the BCL-XL protein to lower the body's platelet levels and increase the risk of bleeding, which significantly reduces that risk researchers point out that PROTAC drugs can effectively treat T-cell malignant , such as T-cell acute leukemia and T-cell lymphoma, an important immune cell produced by the body's thymus, which is essential for the body to produce a suitable immune response to protect against foreign bodies, but when these T-cell cancerous, it will rely on the special protein BCL-XL to survive researcher Dr Peter Houghton says PROTAC drugs can effectively degrade the BCL-XL protein in cancer cells compared to just inhibitions, and that drugs such as PROTAC drugs may be expected to help develop new treatments that can successfully treat specific, difficult-to-treat cancers origins: Khan, S., Zhang, X., Lv, D et al A elective BCL-XL PROTAC degrader afe and potent antitumor activity Nat Med 25, 1938-1947 (2019) doi:10.1038/41591-019-0668-z
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