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Because of their high efficiency, opioids are widely used in the treatment of neuropathic pain, although the proportion of opioid addiction and deaths due to overdose is rising
It is well known that low temperatures numb
To this end, a research team led by Professor Min-Ho Seo of Busan National University has developed a soft, bioresorbable, implantable device that has the potential to cool peripheral nerves
To develop the device, the team designed a microfluidic system consisting of the bioabsorbable material polyoctane glycol citrate, connected to a serpentine cavity
Next, the team tested the device by implanting it into a model of a sciatic nerve in living rats with nerve damage
The device is made of a bioabsorbable material, soaked in a phosphate-buffered saline solution at 75 °C, dissolved in 20 days and eliminated
As this progress progresses, patients with neuropathic pain will eventually be able to receive safe and sustainable treatment without the risk of adverse reactions associated with opioid use!
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reference
Soft, bioresorbable coolers for reversible conduction block of peripheral nerves