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A new study for melanoma patients shows that dietary fiber and probiotics affect the gut bacteria and immunotherapy response of melanoma patients
The human gut microbiota is shaped by a variety of environmental exposures, including diet and drug use
In order to understand how dietary habits affect the microbiota and clinical outcomes of immunotherapy, Christine Spencer and others conducted an observational study that first analyzed the gut microbiota of 438 melanoma patients
Next, they tried to evaluate the effect of dietary fiber intake on ICB response
The authors say that in the context of immune checkpoint blockade therapy, ongoing dietary intervention studies are critical to determine whether targeted and achievable dietary changes at the start of treatment can safely and effectively improve outcomes