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"Science Advances" Live Skin DNA Transfection Platform: Similar to "Cupping" of Traditional Chinese Medicine

 Last Update: 2021-11-11
 Source: Internet
 Author: User

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surface technology

protein level

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The pEGFP-N1 plasmid shows strong GFP expression, and fluorescence can be observed 1 hour after administration

The synthetic SARS-CoV-2 DNA vaccine has proved its specificity.

Nucleic acid-based medicine has been extensively developed in the past two decades, thanks to its prospects in therapeutics and vaccines

In vivo nucleic acid transfection uses viral and non-viral platforms

Current EP devices use strong electric fields of several hundred volts per centimeter to instantaneously penetrate cell membranes and induce cell uptake

A new study published in the journal "Science Advances" reports a new, painless and effective suction-based skin DNA delivery and host cell transfection method, which has a wide range of laboratory and clinical applications Application

Novel suction-based in vivo cutaneous DNA transfection platform

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