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People with severe mental illness (SMI) die approximately 15 years younger than the general population, largely due to higher morbidity and mortality from physical illness in this vulnerable group
The University of Manchester's Department of Psychology and Mental Health, the Manchester Academic Health Sciences Centre Lamiece Hassan and others investigated COVID-19 mortality in patients with schizophrenia and other SMI patients before, during and after the UK vaccine rollout
Using Greater Manchester (GM) care records to obtain routinely collected health data in relation to death records, the study mapped people with schizophrenia/psychosis, bipolar disorder (BD) between February 2020 and September 2021 Changes in COVID-19 mortality over time in GM residents with and/or recurrent major depressive disorder (MDD)
turn out
Mortality from a) COVID-19 and b) other causes compared to pooled controls between March 2020 and September 2021, based on diagnosis
Patients with severe schizophrenia had a significantly higher risk of death, especially those with schizophrenia/psychosis (RR 3.
Mortality ratios due to a) COVID-19 and b) other causes, by diagnosis compared to pooled controls between March 2020 and September 2021
In the adjusted model, the relative risk of death from COVID-19 was reduced in schizophrenia (RR 1.
Patients with severe schizophrenia, particularly those with schizophrenia and bipolar disorder, were at greater risk of death from COVID-19 compared with matched controls
Research to date has consistently shown that people with mental illness, especially those with severe mental illness, are at increased risk for poorer outcomes associated with COVID-19, prompting calls to prioritize screening, treatment, and vaccination for this population
original source
Lamiece Hassan, Chelsea Sawyer, Niels Peek, Karina Lovell, Andre F Carvalho, Marco Solmi, George Tilston, Matthew Sperrin, Joseph Firth, Heightened COVID-19 Mortality in People With Severe Mental Illness Persists After Vaccination: A Cohort Study of Greater Manchester Residents , Schizophrenia Bulletin, 2022; sbac118, https://doi.