Role and efficacy of dimethyl sulfoxide DMSO Uses

Dimethyl sulfoxide, English name DMSO
.

Colorless viscous liquid
.

Hygroscopic
.

It can be miscible with water, ethanol, acetone, acetaldehyde, pyridine, ethyl acetate, dibutyl phthalate, dioxane and aromatic compounds, etc.
, and is insoluble in aliphatic hydrocarbon compounds
other than acetylene.

Dimethyl sulfoxide is widely used as a solution and reaction reagent
.

DMSO has applications in organic synthesis, medicine, electronics and other aspects
.

Dimethyl sulfoxide is particularly used in anhydrous chemical synthesis reactions and pharmaceutical intermediate synthesis reaction solvents
.

The use of this solvent can improve the reaction speed, reaction yield, shorten the reaction time
.

Dimethyl sulfoxide is an organic solvent, with a wide range of dissolution, and has a certain anti-inflammatory and antipruritic effect, and is widely used
as a solvent in the laboratory.

It is also widely used as a permeable cryoprotectant
.

Biologically dimethyl sulfoxide can be used to cryopreservate cells
.

During the freezing and thawing process, the spindle is easily damaged
by ice crystals formed within the cell.

Spindle rotation, pole formation, prokaryotic migration and cell division can be inhibited by cytotares, etc
.

It can work synergistically with DMSO in preventing cryogenic damage
.

Dimethyl sulfoxide has anti-inflammatory, anti-edematous and local analgesic effects
.

The drug has a variety of anti-inflammatory mechanisms of action, the important of which is the ability to inactivate hydroxyl radicals
.

Because hydroxyl radicals can be produced in large quantities during the body's inflammatory response, and lead to tissue necrosis
.

Therefore, dimethyl sulfoxide can improve the metabolism of the affected area and can play an anti-edematous role
to a certain extent.

In addition, the local analgesic effect of dimethyl sulfoxide is due to the ability to slow down the conduction rate of peripheral nerves, through such a mechanism to obtain analgesic effect
.

The harm of dimethyl sulfoxide to the human body DMSO is less toxic, has permeability to human skin, and has a harmful effect
on the eyes.

DMSO has a certain toxic effect, when using it to avoid volatilization, to prepare 1%-5% of ammonia backup, after the skin is stained with a large amount of water washing and dilute ammonia washing.
It is common for discomfort, vomiting, rash and smell
of garlic, onion, and oysters in the skin and exhaled gas.

Inhalation: High volatile concentrations may cause headache, dizziness and sedation
.

Skin: Can burn the skin and make the skin tingling, just like the rash and blisters seen
.

If the dimethyl sulfoxide comes into contact with the aqueous skin, it will produce a thermal reaction
.

Avoid contact with dimethyl sulfoxide solutions containing toxic raw materials or substances, because their toxicity is not well known, while dimethyl sulfoxide may penetrate into the skin, under certain conditions will bring toxic substances into the skin
.

Absorption: The risk of absorption is low
.