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    Home > Biochemistry News > Peptide News > Rheumatoid arthritis associated proteins have been found

    Rheumatoid arthritis associated proteins have been found

    • Last Update: 2013-07-17
    • Source: Internet
    • Author: User
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    A Japanese research team recently found that a protein is related to the excess production of interleukin-6 If it can prevent the protein from playing its role, it is expected to inhibit the imbalance of interleukin-6, and then carry out more effective treatment for rheumatoid arthritis caused by the abnormal cytokine   Rheumatoid arthritis (RA) is a chronic inflammation in which autoimmune disorders cause the immune system to attack the joint IL-6 is considered to play an important role in the pathogenesis of rheumatoid arthritis   Researchers from Osaka University and Kyoto University found that a protein called arid5a is related to the excess production of interleukin-6 They found that the arid5a protein binds to messenger RNA in cells Messenger RNA carries genetic information Usually, the newly produced messenger RNA is easily destroyed by enzymes, but arid5a can block the function of catabolic enzymes, resulting in excessive synthesis of interleukin-6   The discovery is expected to promote the development of cheap rheumatoid arthritis drugs, said Osaka University Professor Tadao Abe Relevant papers have been published in the online edition of the Journal of the National Academy of Sciences.
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