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Retinal Research Laboratory has made new progress in the study of glial cell activation mechanism in glaucoma

 Last Update: 2022-02-22
 Source: Internet
 Author: User

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Glaucoma is the second leading cause of blindness and the leading cause of irreversible blindness
.

The activation of retinal glial cells plays an important role in the pathogenesis of glaucoma, but the mechanism of its activation and interaction has not been fully elucidated

Müller cells and microglia are the main two types of glial cells in the retina
.

The research results of Professor Wang Zhongfeng's team found that in the retina of mice with chronic intraocular hypertension experimental glaucoma, the activation of Müller cells was earlier than that of microglia, and the activated Müller cells released ATP through the connexin-43 hemichannel to act on the microglia.

Over the years, the retinal research laboratory of Fudan University Brain Science Research Institute, led by Academician Yang Xiongli, has paid special attention to the combination of basic research and clinical practice, and has achieved a number of important research results.
mechanism"
.

This research achievement was mainly completed by Ph.

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