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The research published in Nature Communications highlights the development of HySyn, a system that uses neuropeptides from Hydra, a small freshwater organism, to reconnect neural circuits
Researchers created the gene line of mutant C.
Daniel Colón-Ramos, MBL researcher at Yale University School of Medicine, said: "These neuromodulatory peptides allow you to communicate
The researchers used a mutant strain of Caenorhabditis elegans that lacked the neural connections that control specific behaviors—a behavior that tells them that they are full and need to stop looking for food
Hawk said: "There are hundreds of neuropeptides in Hydra, each of which may be a different communication channel
Hawk calls this research a "proof of principle" for the HySyn tool
There are many different types of communication in the brain
Colón-Ramos said: "Usually, we can break things scientifically
Hawk didn't just put back the missing components in the nematode's brain; he introduced a brand new part from Hydra-a set of different parts to repair the damaged part
Hawk said that he hopes that future research will focus on cutting off the communication lines in the brain and reconstructing them in different ways in Hydra
Hawk said: "There are many different synaptic connections in the brain of any animal
Researchers believe that Hydra will play a role in a variety of organisms
Hawk added that he hopes the researchers will focus on understanding the strength of the brain's internal connections
Colón-Ramos said: "Josh was able to use knowledge from MBL and the people he knew, combining all this knowledge with his own interests in neuroscience, and made a significant contribution
"It's like a symbolic MBL project," Colón-Ramos said
Hawk, JD, Wisdom, EM, Sengupta, T.