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Research reveals why elderly people are susceptible to new crowns

 Last Update: 2021-12-02
 Source: Internet
 Author: User

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International war "epidemic" operation

By pneumonia impact of the new crown largest populations, including the elderly and patients with both diseases, including diabetes, hypertension, obesity, metabolic syndrome, cardiovascular disease, chronic obstructive pulmonary disease and asthma

Studies have shown that the level of a protein called "chitinase 3-like protein 1" increases with age, as well as comorbidities and infections

The corresponding author of the study, Dr.

Chitinase 3-like protein 1 is a molecule that occurs naturally in the blood

Researchers say that levels of chitinase 3-like protein 1 also show an increasing trend during normal aging

In the experiment, the researchers used genetically modified model mice to study the relationship between chitinase 3-like protein 1 and ACE2, a key receptor for the new coronavirus to enter human cells

Driven by this discovery, the researchers developed a humanized monoclonal antibody called FRG, which can attack a specific region of chitinase 3-like protein 1

Researchers say the discovery paves the way for the development of treatments that protect people from infection

At present, the research team is observing the response of these antibodies and small molecules to variants of the new coronavirus, including the recently popular delta variant

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