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    Home > Biochemistry News > Biotechnology News > Research on the source of CRISPR-Cas9 reveals a class of RNA-guided nucleases with genome editing potential

    Research on the source of CRISPR-Cas9 reveals a class of RNA-guided nucleases with genome editing potential

    • Last Update: 2021-09-19
    • Source: Internet
    • Author: User
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    The researchers tried to understand the origin of the CRISPR-Cas9 system.
    They discovered a class of transposon-encoded RNA-guided nucleases, which they called "OMEGA", which can be used for genome editing in human cells
    .
    According to the authors, these systems have strong potential for the development of biotechnology


    .


    The author named the system of these new features OMEGA (Obligate Mobile Element Guided Activity)
    .
    They said: "The widespread distribution of the system described here indicates that the RNA-guided mechanism is more widespread in prokaryotes than previously suspected, and that the RNA-guided activity is likely to be ancient and evolved in multiple independent occasions.


    Probably only the most common occasions have been identified so far


    Article published in Science published on September 9

    DOI

    10.


    1126/science.



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