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With the vigorous development of DNA nanotechnology, increasingly complex multifunctional DNA nanostructures have been successfully constructed in a variety of schemes
The first solution is based on the structure of immobile Holliday junctions, which controls the spiral stacking mode of the four-arm branch module through a specific nucleotide sequence at the branch point, thereby realizing the control of the branch direction
Figure 1 The direction control of the four-arm branch module based on the specific nucleotide sequence at the branch point
The second solution uses an angle control pillar to realize the angle control of the flexible four-arm branch module
Figure 2 Angle control of the four-arm branch module based on the angle control pillar
The research results were jointly completed by the Wei Diming Molecular Design Group (MADlab) of the School of Life Sciences of Tsinghua University and the Seaman Group of New York University.
Link to the paper: https://doi.
