Radiology: Temporal Epilepsy and Resting Function Imaging

BACKGROUNDAlthough most refractory temporal lobe epilepsy (TLE) disappeared after the excision of the temporal lobe, about 40% of patients still had seizuresPreoperative restive function imaging MRI may help to classify risk in patients who may have postoperative epilepsy by evaluating functional network integritypurpose
this study was designed to evaluate the correlation between preoperative restive function MRI and postoperative prognosis in patients with refractory TLEmaterials and methods
this study included patients with refractory TLE who had a restive function MRI and a one-sided pre-temporal lobe excisionEESOS was used to classify postoperative seizure-free statesCalculate the overall and regional resting functional MRI network characteristics, using T-test and multi-logistics regression analysis to compare differences between postoperative non-epileptic seizures (Engel graded IA) and other classifications (Engel IB and IV)results40 patients were evaluatedthis studyCompared with patients with no seizures after surgery, there were significant differences between preoperative global networks, with the leaf part being about 9% lower and the tree structure 10% lowerThere were significant differences in the integration of local networks on the lateral temporal lobes before surgeryIn particular, in patients who still had seizures after surgery, the proportion of intra-olfactory cortex-horizontal lobes was 59% lower, 73% lower in the lower tashimi, 43% lower in the temporal lobe, and 69% lower in the island leafThe multiple regression analysis showed that the leaf ratio and epilepsy course of the lateral island area were independent indicators for predicting no seizures after surgery, while age and age at the time of onset could not predict whether there were seizures after surgeryconclusion
the integration of the preoperative restive function MRI show edgtosis and the reduction of network integration of the lateral lobe cortex are associated with seizures in patients with temporal lobe epilepsy