Radiology: Single phase or multiple phases?

 The state of collateral circulation is an important predictor of imaging and clinical prognosis of patients with acute ischemic stroke (AIS) caused by anterior circulation occlusion
.

Although digital subtraction vascular angiography is considered to assess the status of collateral flow standard examination methods, but because the checks are more complicated and longer, it is difficult to promote the use in acute situations

 The state of collateral circulation is an important predictor of imaging and clinical prognosis of patients with acute ischemic stroke (AIS) caused by anterior circulation occlusion

With the development of mechanical thrombectomy, advanced imaging methods have been widely used for baseline assessment

Although multi-phase CT angiography is very valuable in predicting the prognosis of patients with AIS, there are very limited related studies comparing its performance with CT perfusion in this regard

A total of 119 patients (median age 75 years; interquartile range, 66-82 years old; 74 men) were included in this study
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Both single-phase and multi-phase Menon scores were moderately negatively correlated with FIV (r = -0.

Both single-phase and multi-phase Menon scores are moderately negatively correlated with FIV.
Receiver operating characteristic curve analysis shows that multi-phase Menon scores are better than single-phase Menon scores, multi-phase Menon scores and low perfusion volume or ischemia There is no difference between center volumes .
Multivariate analysis shows that the multiphase Menon score is an independent predictor of good clinical prognosis

Figure 1 Receiver operating characteristic curves of the sensitivity and specificity of four CT angiography and CT perfusion predictors in predicting good clinical prognosis
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Figure 1 Receiver operating characteristic curves of the sensitivity and specificity of four CT angiography and CT perfusion predictors in predicting good clinical prognosis
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Table 1 Estimates the sensitivity of the selected specificity based on the receiver's operating characteristic curve
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Table 1 Estimates the sensitivity of the selected specificity based on the receiver's operating characteristic curve
.

This study shows that in patients with acute ischemic stroke, multi-phase CT angiography can predict the prognosis of patients more accurately than single-phase CT angiography in assessing the state of collateral circulation, and the performance has the same effect as CT perfusion parameters.
Comparability
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This study paves the way for the wide application of multiphase CT angiography in patients with acute ischemic stroke

This study shows that in patients with acute ischemic stroke, multi-phase CT angiography can predict the prognosis of patients more accurately than single-phase CT angiography in assessing the state of collateral circulation, and the performance has the same effect as CT perfusion parameters.

Original source:

Zhi Wang , Jian Xie , Tian-Yu Tang ,et al.

Zhi Wang , Jian Xie , Tian-Yu Tang ,et al.
Collateral Status at Single-Phase and Multiphase CT Angiography versus CT Perfusion for Outcome Prediction in Anterior Circulation Acute Ischemic Stroke .
DOI: 10.
1148/radiol.
2020192029 10.
1148/radiol.
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