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The brain is the most commonly affected extrathoracic organ in patients with non-small cell lung cancer ( NSCLC
) .
Brain metastases are found at initial presentation in approximately 10% to 20% of patients, and metastatic disease is strongly associated with poor prognosis
The brain is the most commonly affected extrathoracic organ in patients with non-small cell lung cancer ( NSCLC
Seoul National University Hyungjin Kim Hyungjin Kim et al .
published a research article in the journal Radiology Radiology , which explored whether preoperative brain MRI examinations benefited asymptomatic patients with early-stage non-small cell lung cancer .
Patients with T1N0M0 NSCLC who underwent radical resection between February 2009 and March 2016 were retrospectively included
.
Patient survival and development of brain metastases during postoperative monitoring were recorded
Patients with T1N0M0 NSCLC who underwent radical resection between February 2009 and March 2016 were retrospectively included
A total of 628 patients (mean age, 64 ± 10 years; 319 men) were included in the study, 53% of whom underwent brain MRI staging
In multivariate analysis, brain MRI did not show significant differences in brain metastasis-free survival (hazard ratio [HR], 1.
06; 95% CI: 0.
69, 1.
In multivariate analysis, brain MRI did not show significant differences in brain metastasis-free survival (hazard ratio [HR], 1.
Cumulative survival curves and cumulative incidence plots of clinical stage IA non-small cell lung cancer patients, stratified according to preoperative brain MRI staging findings
.
(A) Brain metastasis-free survival (log-rank test P.
Cumulative survival curves and cumulative incidence plots of clinical stage IA non-small cell lung cancer patients, stratified according to preoperative brain MRI staging findings
In conclusion, no differences were observed in brain metastasis-free survival, brain metastasis time, and overall survival between patients with asymptomatic clinical stage IA NSCLC who underwent brain MRI staging and those who did not undergo brain MRI staging
original source
Nam JG, Hong H, Choi SH, et al.
Nam JG, Hong H, Choi SH, et al.
No Prognostic Impact of Staging Brain MRI in Patients with Stage IA Non-Small Cell Lung Cancer [published online ahead of print, 2022 Mar 8].
Radiology .
2022;212101.
doi: 10.
1148/radiol.
212101 Nam JG, Hong H, Choi SH, et al.
No Prognostic Impact of Staging Brain MRI in Patients with Stage IA Non-Small Cell Lung Cancer [published online ahead of print, 2022 Mar 8].
Radiology here message
