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Information about normal diffusion-weighted imaging patterns in early childhood development is very limited
Information about normal diffusion-weighted imaging patterns in early childhood development is very limited
Previously, the understanding of the normal development of ADCs was limited to two-dimensional image analysis, and there were few MRI scans of full-term and normally developing children, especially longitudinal studies on children 2 years of age or younger
Recently, a study published in the journal Radiology quantitatively analyzed the normal apparent diffusion coefficient (ADC) development pattern of children aged 0 to 6 years, and explored the temporal and spatial heterogeneity of ADC values and differences in the development of the cerebral hemispheres, providing clinical information An ADC model that accurately divides the three-dimensional regions of the developing brain and can simulate changes over time is conducive to the further elucidation and early diagnosis of the mechanism of various diseases in the clinic
Hindlimb of internal capsule (average ADC: left hemisphere, 1.
Chart view of diffusion coefficient (ADC) voxel analysis of mature age
This study quantified the standard apparent diffusion coefficient development pattern of children aged 0-6 on MRI diffusion-weighted scans, and proposed a comprehensive analysis of changes in diffusion-weighted imaging based on a three-dimensional map, which solved the previous lack of Knowledge of changes in the apparent diffusion coefficient in the early regions of brain development and age
Original source:
Susan Sotardi , Randy L Gollub , Sara V Bates ,et al.
