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On June 3, Prism Pharmaceuticals issued an announcement stating that it had recently received a notice of approval of Pantoprazole Sodium for Injection issued by Health Canada.
Pantoprazole Sodium for Injection is a selective long-acting proton pump inhibitor.
The persulfoxide group is connected to the pyridine ring, which is relatively stable under neutral and weak acidic conditions, and is rapidly activated under strong acidic conditions, so that it has better selectivity for H+ and K+-ATPase.
This product can specifically inhibit the secretory microtubules formed by the apical membrane of parietal cells and the H+ and K+-ATPases on the tubular vesicles in the cytoplasm, causing irreversible inhibition of the enzymes, thereby effectively inhibiting the secretion of gastric acid.
It is suitable for active peptic ulcer (gastric, duodenal ulcer), reflux esophagitis and Zollinger-Ehrlich syndrome.