Protective effect of turmeric extract on apoptosis of sk-n-sh cells induced by Na 2S 2O 4
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Last Update: 2014-04-28
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Source: Internet
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Author: User
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Recently, researchers from Bethune International Peace Hospital of PLA published a paper to observe the protective effect of turmeric extract on apoptosis of sk-n-sh cells induced by Na2S2O4 and its mechanism It was pointed out that turmeric extract could inhibit the apoptosis of sk-n-sh cells by Na2S2O4 through antioxidation This article was published in the 02 issue of the Journal of modern integrated Chinese and Western medicine in 2014 Sk-n-sh cells of the same generation were randomly divided into normal control group, model group, low concentration of turmeric extract (20 μ mol / L), medium concentration of turmeric extract (40 μ mol / L) and high concentration of turmeric extract (80 μ mol / L) The effects of turmeric extract on SOD and MDA were detected by spectrophotometry, cell survival rate by MTT colorimetry, apoptosis rate by TUNEL, and caspase-3 protein expression by Western blot Compared with the model group, the cell survival rate of each group increased (P < 0.01), the MDA level in sk-n-sh cell culture medium of each group decreased significantly (P < 0.01), while the SOD level increased significantly (P < 0.01), and the caspase-3 activity was inhibited.
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