Academician Ge Junbo of the Department of Cardiology, Zhongshan Hospital Affiliated to Fudan University, Chief Physician Huang Zheyong, and Pang Zhiqing , an associate researcher of the School of Pharmacy of Fudan University, jointly developed a new RNA nano-targeted delivery platform for regulating the inflammatory response after myocardial infarction and improving myocardial weight Structure
Pang Zhiqing co-developed a new RNA nano-targeted delivery platform for regulating the inflammatory response after myocardial infarction and improving myocardial remodeling
In recent years, RNA therapy has been tried for tissue regeneration and repair research, and it has been found that miRNA-21 can promote the transformation of macrophages to repair type
In this research, Ge Junbo's team built a sophisticated core-shell structured nano-targeted delivery platform for the delivery of small therapeutic RNA
The nano-targeted delivery platform takes into account the RNA protection, targeting, and loading and delivery efficiency in the RNA delivery process, has shown good performance in regulating the inflammatory response of cardiovascular diseases, and has a certain potential for clinical transformation
Related paper information: https://doi.
https://doi.
org/10.
1002/advs.
202100787
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