Professor Xu Yan's team of Jiangnan University Professor Nie Yao's research group published a computer-aided understanding in Biotechnology Advances

Responsible Editor: Food Science

Enzymes have chemoselectivity, regioselectivity and stereoselectivity, thus enabling asymmetric synthesis of chiral molecules

The article first elaborates on the application of the two most commonly used QM calculation methods in the theoretical calculation of enzyme selectivity, the hybrid quantum mechanics/molecular mechanics method (QM/MM) and the quantum chemical cluster method (QM-Cluster).

This work was jointly funded by the National Natural Science Foundation of China (21676120, 31872891), the National Light Industry Technology and Engineering First-class Discipline Project (LITE2018-09) and other projects

Vice President of Jiangnan University

Xu Yan, Professor, Doctoral Supervisor, Vice President of Jiangnan University, Fellow of the Agricultural and Food Chemistry Department of the American Chemical Society (ACS), Development Plan Team Leader of the Innovation Team of the Ministry of Education's Talent Plan of the Same Level, the First Batch of New Century Excellent Talents of the Ministry of Education, National outstanding teachers, enjoy the special government allowance of the State Council

Professor Xu Yan is mainly engaged in scientific research in the field of brewing science and industrial enzymology.

Professor Xu Yan has successively presided over 18 national-level major scientific research projects such as the National 13th Five-Year Key R&D Program, "973 Program", "863 Program", National Science and Technology Support Program, and National Natural Science Foundation of China (Key Project)

Professor Xu Yan currently serves as the director of the Center for Brewing Science and Enzyme Technology of Jiangnan University, the vice chairman of the China Alcoholic Drinks Association, the deputy director of the Liquor Technical Committee of the China Brewing Industry Association, and the chairman of the China Distilled Wine Industry Technology Innovation Strategy Committee

School of Bioengineering, Jiangnan University

Nie Yao, professor and doctoral supervisor
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He has been engaged in research on the theory and application of microbial molecular enzymology and catalytic engineering for a long time
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In recent years, he has published more than 100 high-level research papers, cited more than 600 times, and published 3 monographs (or teaching materials); applied for 24 invention patents, and authorized 16 invention patents, including 1 international invention patent; 12 provincial and ministerial-level scientific research projects, including the National Natural Science Foundation of China, the National Key R&D Program, the 973 Project, the 863 Project, and the Natural Science Foundation of Jiangsu Province; won the Outstanding Contribution Award for Youth in Science and Technology by Sinopec Federation (2019) , the first prize of the Ministry of Education Technology Invention Award (2009), the first prize of the Sinopec Federation Technology Invention Award (2017), the second prize of the Jiangsu Science and Technology Award (2014), the China Industry-University-Research Promotion Association Innovation Achievement Award (2011), etc.
Research awards
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Selected into the National "Special Support Program" Young Top Talents, Jiangsu Province's "Six Talent Peaks", Jiangsu Province "Blue Project" young and middle-aged academic leaders, Jiangsu Province "333 Project" young and middle-aged science and technology leaders and other talent projects
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He is also a standing member of the Biochemical Professional Committee of the Chinese Chemical Society, a guest editor of Systems Microbiology and Biomanufacturing , and an editorial board member of academic journals such as Frontiers in Bioengineering and Biotechnology , Bioresources and Bioprocessing , and Fungal Biology and Biotechnology
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