Preventive effect of Schisandra chinensis water extract on oxidative stress injury of rat hepatocytes induced by microwave radiation

Recently, researchers from biochemistry and molecular biology teaching and research section of Jilin Medical College published a paper to explore the effect of Schisandra chinensis water extract on preventing oxidative stress injury of rat hepatocytes caused by microwave radiation, and to clarify the prevention and protection of Schisandra chinensis water extract on microwave induced liver injury The results showed that 200MW · cm-2 microwave radiation could cause the oxidative stress level and the morphological changes of liver cells in rats, while the water extract of Schisandra chinensis could prevent the damage of liver cells in Wistar rats This article was published in the Journal of Jilin University (Medical Edition), the 6th issue in 2013 Thirty six normal adult Wistar rats were randomly divided into normal control group, microwave radiation group and Schisandra chinensis water extract prophylactic administration group, with 12 rats in each group Water extract of Schisandra chinensis was given to rats in the prevention and administration group for gastric administration After 5 days and microwave radiation group, microwave radiation was carried out MDA concentration and SOD activity in liver tissue of rats in each group were detected at 0 and 16 hours after microwave radiation, and he staining was used to observe the morphology of liver tissue and cells of rats in each group Compared with the normal control group, there was no significant change in MDA concentration and SOD activity in the liver tissue of rats in the microwave radiation group at 0 h after irradiation, but MDA increased and SOD activity decreased significantly in the microwave radiation group at 16 h after irradiation (P < 0.05); compared with the microwave radiation group at 16 h after irradiation, the MDA concentration and SOD activity of rats in the Schisandra chinensis water extract prevention group decreased and increased (P < 0.05) Microwave radiation caused obvious edema of rat hepatocytes, while Schisandra chinensis water extract can significantly alleviate the edema of rat hepatocytes caused by microwave radiation.