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a major international study, it is much better to open all blocked arteries with a stent after a severe heart attack than to open only the single blocked arteries that cause a heart attack.
In addition to the arteries that cause heart attacks, about half of heart attack victims have other arterial blockages. Previously, doctors focused on opening an artery that causes a heart attack, leaving other obstructions to be treated with medication. The new study, conducted in collaboration with 130 hospitals in 31 countries, found that it was better to open all the blockages than to treat only the single blockage that causes a heart attack. This reduced the risk of death or recurrent heart attacks by 26 percent.
Today, a study called the COMLETE Trial was published in the New England Journal of Medicine and presented as the latest clinical science conference at the European Society of Cardiology Conference and the World Congress of Cardiology in Paris, France.
“ Given its size, international reach, and patient-centered results, this COMPLETE trial will change the way doctors treat the disease and prevent thousands of recurrences of heart disease worldwide each year," said Dr. Shamir R. Mehta, director of population health research at McMaster University and the Hamilton Institute for Health Sciences.
He said that while it was known that it would be beneficial to open a single blocked artery that causes a heart attack, it was not clear whether additional stents were needed to remove other blocked arteries from blocked death or heart disease. In most cases, the doctor will only use medication to treat the additional obstruction.
“ This study clearly shows that there are long-term benefits to preventing severe heart-related events by removing all arteries. There are no significant negative effects from other operations," Mehta said.
The COMPLETE trial, led by PHRI and funded by the Canadian Institutes of Health and involving 4,041 patients, was the first large randomized international trial to show a decrease in the main results of the method.
“ The long-term benefits are obvious, similar to any additional stent surgery at any time in the first 45 days after a heart attack," said Mehta, a senior PHRI scientist, professor of medicine at McMaster University and an interventionist and cardiologist at Hamilton Health Sciences.
Mehta said that in a three-year mid-life period, the second heart attack or cardiovascular mortality rate dropped to 7.8
percent
percent of patients with complete blood reconstruction, compared with 10.5 percent of patients who had an arterial stent for the first heart attack, a significant difference. This benefit is even greater when other adverse events are taken into account, such as severe chest pain that requires repeated stentization.
There was no difference between the two groups on whether patients would experience side effects, including stroke and haemorrhage. (cyy123.com)