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Tissue-resident white blood cells use glucose as an energy source to fight infection, new study finds
A new study, led by Associate Professor Marc Veldhoen of the Faculty of Medicine of Lisbon (FMUL) and published in PNAS, finds that white blood cells in the gut are specialized immune cells called "tissue-resident lymphocytes" that use sugar as a The energy source is metabolized faster than the lymphocytes circulating in the bloo.
Lymphocytes are known to circulate in blood vessels in the body and function as a surveillance system, but there is also a special group of lymphocytes that reside permanently in tissue.
"Circulating lymphocytes spend most of their life in the lymph nodes, where there is a lot of energ.
To test whether glucose plays a role in the immune response to infection, the researchers used a mouse model of intestinal infectio.
