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    Home > Biochemistry News > Biotechnology News > PLOS: How the enteric nervous system affects the gut microbiome

    PLOS: How the enteric nervous system affects the gut microbiome

    • Last Update: 2022-03-07
    • Source: Internet
    • Author: User
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    A new study from the University of Oregon shows that nerves in the gut help regulate the acidity of the gut


    "We found an unexpected link between the enteric nervous system and the gut microbiome," said UO microbiologist Karen Guillemin


    Gillette led the new work with Ohio State neuroscientist Judith Eisen


    Scientists have known for years that gut bacteria are important to digestive health


    To make this connection, Eisen and Gillette studied a zebrafish with a genetic mutation that caused the loss of nerves in the gut


    Eisen and Guillemin have previously shown that zebrafish lacking intestinal nerves have similar inflammation


    Input: Zebrafish


    Postdoctoral researcher Kristi Hamilton came with a hunch—she suspected that the diseased zebrafish might have something wrong with their gut pH


    Giving fish a heartburn medication called omeprazole (omeprazole is commonly known as omeprazole) can relieve stomach acid and restore bacterial balance


    The findings suggest that not only do nerves in the gut control the contractions that keep the gut moving, they also help regulate gut acidity, ensuring a healthy bacterial population


    Journal Reference :

    1. M.




    University of Oregon.



    University of Oregon.



    University of Oregon.
    "How the intestine's nervous system affects gut microbes: Research uses a common heartburn medication in zebrafish to alter gut acidity and change microbial communities.
    " ScienceDaily.
    ( accessed February 14, 2022).


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