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Pharmaceutical-grade polyethylene caprolactam-polyvinyl acetate-polyethylene glycol graft copolymer Soluplus

 Last Update: 2022-10-01
 Source: Internet
 Author: User

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high temperature furnace

refractory

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Pharmaceutical grade polyethylene caprolactam - polyvinyl acetate - polyethylene glycol grafting copolymer Soluplus Soluplus (polyethylene caprolactam - polyvinyl acetate - polyethylene glycol grafting copolymer) is a new type of amphiphilic non-ionic pharmaceutical polymer material, glass conversion temperature (Tg) about 70 °C, high safety, with solubilization, crystallosis, spatial stability, suspension, heat sensitivity, film formation and other effects, It has shown good application prospects in improving the dissolution rate and bioavailability of refractory drugs.
This paper reviews the application progress of Soluplus in solid dispersions, polymer micelles, drug nanocrystals, supersaturated autoemulsification delivery systems, etc.
, and also points out that Soluplus has limited
scope due to low Tg value and strong hydrophilicity.

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