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Pharmaceutical grade mixed fatty acid glyceride 36 type suppository base molding auxiliary material mixed fatty acid glyceride (stearyl) mixed fatty acid glyceride (stearyl) is a mixture of mono-, di- and tri-glycerides of C8~C18 saturated fatty acids
.
Mixed fatty acid glycerides (stearin) are white or off-white waxy solids; have a greasy odor
.
Mixed fatty acid glycerides (stearyl), soluble in petroleum ether (60~90℃), almost insoluble in water or ethanol
.
Melting point The melting point of this product (general rule 0612 second method) is: 34 type 33~35℃; 36 type 35~37℃; 38 type 37~39℃; 40 type 39~41℃
.
Acid value The acid value of this product (general rule 0713) should not be greater than 1.
0
.
Hydroxyl Value The hydroxyl value of this product (General Rule 0713) should not be greater than 60
.
Iodine value The iodine value of this product (general rule 0713) should not be greater than 2.
0
.
Peroxidation value The peroxide value of this product (general rule 0713) is not greater than 3
.
Glycerol fatty acid esters generally refer to fatty acid glycerides, which are obtained by esterification of fatty acids (RCOOH) and glycerol (C3H8O3) under the action of catalysts
.
Different glycerides can be prepared using different fatty acids
.
The reaction formula is: RCOOH catalyst-0.
1MPa C12H24O2 C18H36O2 C3H8O3 C3H5O3 (COR) 3 H2O 218 ℃ fatty acid glyceride is slightly acidic, almost no hydrolysis in neutral water (PH=6-7), but a small amount of acid Or the presence of alkali, the hydrolysis reaction rate increases
.
It is easily soluble in benzene, soluble in petroleum ether, and almost insoluble in water or ethanol
.
Hydrolysis reaction: The fatty acid ester is slightly acidic, and almost no hydrolysis occurs in neutral water (PH=6-7), but there is a small amount of acid or alkali, and the hydrolysis reaction speed increases
.
Oxidation reaction: At normal temperature, saturated fatty ester hardly undergoes oxidation reaction, and at high temperature above 100°C, it can be slowly oxidized to generate peroxide, and ketone or hydroxyl compound is generated
.
Thermal Decomposition: Fatty acids undergo thermal decomposition at high temperatures to form carboxylic acids and olefins
.
.
Mixed fatty acid glycerides (stearin) are white or off-white waxy solids; have a greasy odor
.
Mixed fatty acid glycerides (stearyl), soluble in petroleum ether (60~90℃), almost insoluble in water or ethanol
.
Melting point The melting point of this product (general rule 0612 second method) is: 34 type 33~35℃; 36 type 35~37℃; 38 type 37~39℃; 40 type 39~41℃
.
Acid value The acid value of this product (general rule 0713) should not be greater than 1.
0
.
Hydroxyl Value The hydroxyl value of this product (General Rule 0713) should not be greater than 60
.
Iodine value The iodine value of this product (general rule 0713) should not be greater than 2.
0
.
Peroxidation value The peroxide value of this product (general rule 0713) is not greater than 3
.
Glycerol fatty acid esters generally refer to fatty acid glycerides, which are obtained by esterification of fatty acids (RCOOH) and glycerol (C3H8O3) under the action of catalysts
.
Different glycerides can be prepared using different fatty acids
.
The reaction formula is: RCOOH catalyst-0.
1MPa C12H24O2 C18H36O2 C3H8O3 C3H5O3 (COR) 3 H2O 218 ℃ fatty acid glyceride is slightly acidic, almost no hydrolysis in neutral water (PH=6-7), but a small amount of acid Or the presence of alkali, the hydrolysis reaction rate increases
.
It is easily soluble in benzene, soluble in petroleum ether, and almost insoluble in water or ethanol
.
Hydrolysis reaction: The fatty acid ester is slightly acidic, and almost no hydrolysis occurs in neutral water (PH=6-7), but there is a small amount of acid or alkali, and the hydrolysis reaction speed increases
.
Oxidation reaction: At normal temperature, saturated fatty ester hardly undergoes oxidation reaction, and at high temperature above 100°C, it can be slowly oxidized to generate peroxide, and ketone or hydroxyl compound is generated
.
Thermal Decomposition: Fatty acids undergo thermal decomposition at high temperatures to form carboxylic acids and olefins
.
