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    Home > Medical News > Latest Medical News > Pfizer's PF-06882961 clinical trial application was approved for the treatment of type 2 diabetes

    Pfizer's PF-06882961 clinical trial application was approved for the treatment of type 2 diabetes

    • Last Update: 2021-03-27
    • Source: Internet
    • Author: User
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    On March 17, the CDE official website showed that Pfizer's PF-06882961 tablet (danuglipron) clinical trial application has been granted the default permission, and it plans to conduct clinical research on the treatment of type 2 diabetes.


    Danuglipron (code name: PF-06882961 tablets) is an oral small molecule GLP-1 receptor agonist developed by Pfizer.


    The potential advantages of danuglipron include: ① It can achieve effective control of blood sugar and weight; ② Tolerability and safety are similar to peptide GLP-1RA, and the oral dosage form is convenient to take; ③ Good bioavailability; ④ Different from oral macromolecules GLP-1RA is not restricted by food or dosage.


    Pfizer announced at the online Investor Day event (Investor Day) held in August 2020

    danuglipron Phase I clinical study data.


    At present, Pfizer has launched a phase II clinical study to test the effect of danuglipron in the treatment of diabetic patients.


    Prior to this, Novo Nordisk Rybelsus (oral smeglutide, once a day) has been approved for marketing by the FDA and is currently the only oral GLP-1 receptor agonist on the market.


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