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In March 2022, the research results of the team of Professor Li Zhanguo from Peking University People's Hospital "Double-blind, randomized, controlled study of the efficacy and safety of low-dose IL-2 combined with methotrexate in the treatment of rheumatoid arthritis" (Efficacy and safety of Ld -IL2 in combination with MTX in patients with active RA: a randomized trial) was published online in the authoritative academic journal Signal Transduction and Targeted Therapy (STTT, IF 18.
Studies have demonstrated the efficacy and safety of low-dose IL-2 in the treatment of rheumatoid arthritis
In this study, patients with active RA were included in a double-blind, randomized, placebo-controlled study, treated with low-dose IL-2 for 3 consecutive months, and followed up for 3 months
Clinical efficacy and evaluation indexes of low-dose IL-2 in the treatment of rheumatoid arthritis
Further analysis in this study found that the treatment was effective in patients with refractory RA with vasculitis
Dr.