Past and present life of medicinal excipients Lecithos

I believe that everyone is not too unfamiliar with lecithin.
As a mixture of various phospholipids with phosphatidylcholine as the main component, it is defined by USP NF as a mixture of acetone-insoluble phospholipids.
Now it is used as a pharmaceutical excipient.
is used
.

But do you really know about the "past life" of this medicinal excipient (lecithin)? The editor will come to give you a good talk about the "past life and present life" of lecithin! As early as the 19th century, the Frenchman Gohley found it in the egg yolk and named it Lecithos (lecithin) in Greek, and the generic name was Lecithin
.

It was later discovered that such a mixture of phospholipids was also present in soybeans
.

Now in order to distinguish the source, it is usually divided into two types: lecithin or egg lecithin, and soybean lecithin, but they are often called lecithin and cannot be distinguished, and even sometimes phosphatidylcholine is also called lecithin.
Referred to as lecithin
.

In fact, different sources and purities of lecithin have very different chemical compositions and uses, and CAS is different
.

The CAS of Lecithin is 8002-43-5, which is defined as phosphatidylcholine in all animal and plant tissues, which can be used as lubricants, emulsifiers, and food additives; the CAS number of soybean lecithin is 8030-76-0, which is extracted from soybean The phospholipid mixture is mainly used for health care products and non-injection drugs.
The CAS number of egg yolk lecithin is 93685-90-6, which is defined as the phospholipid mixture extracted from egg yolk.
It is mainly used for injection-grade pharmaceutical excipients
.

Therefore, when we get a lecithin, we must figure out its source, purity and composition, and then decide how to use it
.

After reading the article, do you know more about this "old man" from the 19th century? Aiweituo (Shanghai) Pharmaceutical Technology Co.
, Ltd.
has been focusing on complex injection fields such as liposomes, fat emulsions, micro-nano targeted preparations, and biological preparations for more than ten years
.

It has developed a characteristic sales model of "university + research institute + enterprise"
.

AVT brings you a variety of medical excipients lecithin, including but not limited to: high-purity egg yolk lecithin PC-98T, egg yolk lecithin PL-100M, hydrogenated soybean lecithin HSPC, egg yolk phosphatidylglycerol EPG, hydrogenated egg lecithin Soy phosphatidylglycerol PGSH, soy lecithin PGSH, soy lecithin Soy-PC, egg yolk sphingomyelin e-SPM.
.
.