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On January 3, 2022, Ovid Therapeutics announced that it had entered into an exclusive license agreement with AstraZeneca to acquire AstraZeneca's early development stage small molecule library targeting the KCC2 transporter, including lead candidate OV350
KCC2 is a potassium chloride cotransporter responsible for maintaining chloride homeostasis in neurons
Under the terms of the agreement, AstraZeneca will receive an upfront payment of $5 million and Ovid stock worth $7.
References:
[1] Ovid Therapeutics Expands Epilepsy Franchise with Novel KCC2 Activators.
(WuXi AppTec)