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Author: Bai Lu
On December 20, Lineage Cell Therapeutics announced that it has signed an exclusive global collaboration and license agreement with its subsidiary Cell Cure Neurosciences and Roche subsidiary Genentech to jointly develop and commercialize retinal pigment epithelium (RPE) cell therapies for the treatment of eye diseases, Including advanced dry age-related macular degeneration (AMD) with geographic atrophy (GA)
Genentech will be responsible for further clinical development and commercialization of Lineage's OpRegen® program, which is currently being evaluated in a Phase I/IIa open-label, dose-escalation clinical safety and efficacy study in patients with advanced dry AMD and GA
OpRegen® is an allogeneic RPE cell transplantation therapy
References:
1# Retinal Tissue Restored in Patients with Dry AMD, Heralding Paradigm Shift (Source: BioSpace)
2# Roche adds to Genentech's ophthalmology program with $670M in biobucks for Lineage Cell Therapeutics' asset (Source: FIERCE Biotech)
3# LINEAGE ESTABLISHES EXCLUSIVE WORLDWIDE COLLABORATION WITH GENENTECH FOR THE DEVELOPMENT AND COMMERCIALIZATION OFOPREGEN® RPE CELL THERAPY FOR THE TREATMENT OF OCULAR DISORDERS (Source: Lineage Cell Therapeutics official website)