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Clinical history
Female, 4 years old
.
New-onset right hand tremor, ataxia, and headache for several days
.
Image [Image Representation]
Axial CT scan with contrast (Figure A) shows a mildly enhanced, expansive growing mass opacity of the pons, with lesions compressing adjacent to the four ventricles
.
Axial T2WI (Figure B) showed that the boundaries of pontine lesions were not clear, infiltrating growth, and hyperintensity
.
The pontine expansive mass is enhanced in the sagittal position of T1WI (Figure C) as a central patchy enhancement
.
【Imaging diagnosis】
Diffuse Intrinsic Pontine glioma (DIPG)
【Discussion】
Endophytic diffuse pontine glioma (DIPG) is the most common brainstem glioma
.
The mean age at onset was 6.
5 years, and the mean survival was less than 1 year
.
It is closely related to neurofibromatosis type 1, with a slow growth cycle and a good
prognosis.
Clinical features: ataxia, dysarthria, and intention tremor
.
Sometimes signs and symptoms
of hydrocephalus occur.
Typical symptoms are short-lived and rapidly progressive
.
Imaging findings: The typical MR of endophytic diffuse pontine glioma (DIPG) is that the infiltrative growth of the pons on T2/FLAIR images occupies most of
the pons.
Lesions are often mildly intensified
.
DWI is often unrestricted
.
