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    Home > Biochemistry News > Biotechnology News > O-glycan sialylation defines breast cancer stem cell population

    O-glycan sialylation defines breast cancer stem cell population

    • Last Update: 2022-01-26
    • Source: Internet
    • Author: User
    Tags

    inductive breast cancer

    mesenchimal stem cells
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    Summary

    We investigated a hypothesis that specific glycans can be used to differentiate breast cancer stem cells (CSCs) and affect their function


    Comparing CSCs and non-CSCs from multiple breast cancer models, it was found that CSCs differed by the expression of α2,3 sialylated core2o-linked glycans


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