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The NRG oncology clinical trial NRG-lu002 compares local consolidation therapy (LCT) and maintenance system therapy for localized metastatic non-small cell lung cancer (NSCLC) with maintenance system therapy alone, and has recently reached the level of the study's Phase II trial.
The Phase 2 study of NRG-LU002 accumulates patients with limited metastatic NSCLC who have completed at least 4 cycles of first-line systemic therapy and have no signs of progression, and divide the patients into squamous or non-squamous disease stratification, and previous systemic treatment options
"Although maintenance system therapy has shown a significant improvement in the survival outcome of patients with metastatic NSCLC, the improvement of local control by local therapy may further stabilize the disease and prolong the life of patients with limited metastasis after initial treatment
If the trial restarts, the question of the third phase of the study will examine whether adding LCT to maintenance system therapy can improve the overall survival of patients with limited metastatic NSCLC
"NRG Oncology expresses its gratitude to the National Clinical Trial Network sites and researchers for their diligent work during the pandemic to accumulate patients for this trial.
NRG Oncology will send an e-mail broadcast when the decision to reopen the proceeds of the NRG-lu002 Phase III research question is made