NPPB protein plays a key role in itching
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Last Update: 2013-08-01
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Source: Internet
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Author: User
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When NPPB protein was injected, mice began to itch Body itching was once thought to be a low-level form of pain, but a recent experiment shows that the whole process of body itching transmission is a complete specialized neural circuit, the journal Nature reported this morning Expert research has revealed the sensory neurons that transmit and receive itch Neuroscientist mark Hoon and Mishra of the National Institute of dental Craniofacial Research in Maryland conducted experiments on mice By touching mice, they found a protein called NPPB, which only works on a subset of these sensory neurons The results showed that there was no response to itch inducing compounds, but there was response to heat and pain in NPPB deficient mice When scientists injected NPPB protein into mice, both the mutant mice and the control mice kept scratching their bodies Mark Xun said that the mechanism of itching in human body is similar, and the next experiment will be carried out in human body.
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