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    Home > Medical News > Latest Medical News > Novartis' new-generation drug Beovu Phase 3 MERLIN study: Intraocular inflammation is higher than aflibercept

    Novartis' new-generation drug Beovu Phase 3 MERLIN study: Intraocular inflammation is higher than aflibercept

    • Last Update: 2021-06-05
    • Source: Internet
    • Author: User
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    Common reasons for abandoning treatment.


    It is worth mentioning that Beovu is the first to have an efficacy comparable to Eylea (aflibercept), and to maintain a 3-month dosing interval after a 3-month loading phase in eligible wet-AMD patients.


    The active pharmaceutical ingredient of Beovu is brolucizumab (RTH258), which is a humanized single-chain antibody fragment (scfv) that targets all types of vascular endothelial growth factor-A (VEGF-A).


    In China, Beovu has entered Phase 3 clinical research, developed for indications such as wet AMD and diabetic retinopathy.


    During the "Never Ending" International Innovative Medicine and Equipment Exhibition, Beovu completed the first injection in the country in the Hainan Boao Super Hospital for the treatment of wet AMD.


    Original source: Novartis reports one year results of Phase III MERLIN study evaluating Beovu® every four week dosing and provides update on Beovu clinical program

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